The Mucus Slurper consists of a modified tracheal tube and an external controller to automatically activate synchronous tracheal aspiration. This protocol was approved by the Animal Care and Use Committee of the National Institutes of Health . In studies in sheep lasting 24 h the Mucus Slurper was safe and prevented all mucus accumulation within the ETT. The tracheal tube and proximal trachea free of mucus. The Mucus Slurper is a novel device designed to keep The tracheal tube was free of tracheal secretions in the Mucus Slurper group while thin secretions were found within the ETT in the control group. During the course of single aspiration the Mucus Slurper never affected the level of applied PEEP. In vivo: during mechanical ventilation we aspirated through the Mucus Slurper 13.4 ± 3.3 cc mucus/24 h. In vitro: with the Mucus Slurper connected toĪ source of vacuum of 450–500 mmHg the total volume of a single suction lasting 0.1, 0.2, and 0.3 s was, respectively, 75.4 ± 7.9, 114.5 ± 4.6, and 143.4 ± 8.7 ml with the measured vacuum within the lumen of the Mucus Slurper ring of 37 cmH 2O. We evaluated the Mucus Slurper in vitro, and we evaluated its efficacy and safety in three healthy sheep during 24 h on volume-controlled mechanical ventilation in comparison to three sheep managed with open tracheal tube suctioning. Six sheep, sedated, paralyzed, and mechanically ventilated Interventions In vitro, and in vivo studies in sheep at the National Institutes of Health, NHLBI, PCCMB. We devised the Mucus Slurper as an integral part of the tracheal tube to aspirate all mucus automatically at its distal tip. The buildup of mucus within the endotracheal tube (ETT) progressively reduces its internal volume.
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